Renseignements généraux

Nº de série

B067

Nº de partie

1

Nombre total de parties

5

Ou

Gene Machine

Brevets

S/O

Description générale

A metal case, with synthetic and metal computer components, metal hardware, synthetic keyboard and control buttons, metal connectors on right side of case, on back of case a metal connector, metal fuse, synthetic cables, wires and paper.

Dimensions

Remarque : Cette information reflète la taille générale pour l’entreposage et ne représente pas nécessairement les véritables dimensions de l’objet.

Longueur

46,0 cm

Largeur

68,7 cm

Hauteur

19,5 cm

Épaisseur

S/O

Poids

S/O

Diamètre

S/O

Volume

S/O

Lexique

Groupe

Technologie médicale

Catégorie

Matériel médical

Sous-catégorie

S/O

Fabricant

Ou

Bio Logicals

Pays

Canada

État/province

Ontario

Ville

Ottawa

Contexte

Pays

Canada

État/province

Ontario

Période

1982+

Canada

Kelvin Ogilvie and his McGill University colleagues demonstrated the foundation chemistry for carrying out the repetitive steps and the automation needed for assembling sequences of DNA. He and his collaborators at Bio Logicals Inc., among them, Robert Bender and Peter Duck, developed the “gene machine,” a device which automated the complex process of building DNA sequences. The research that went into the development of the gene machine was a significant contribution to the genomic revolution of the 1980s and 1990s, and an important part in bringing the "tech" into biotechnology. [see acq. proposal in sup. info for the entire Canadian significance]

Fonction

The Bio Logicals, DNA/RNA Synthesizer (Gene Machine) was used to synthesize sequences of DNA and RNA through an automated process.

Technique

The gene Machine was a major step in automating and speeding up the process for synthesising DNA. In the summer of 1986, the Gene Machine was adapted to prepare RNA. The RNA strand that was initially assembled was the 78-nucleotide-long formylmethionine tRNA (transfer ribonucleic acid) that initiates the synthesis of proteins in cells. Reported in Science and the Proceedings of the National Academy, USA, this breakthrough contributed to the field of genetic engineering and a variety of pharmaceutical and industrial applications including short RNA sequence therapies and "antisense chemotherapy".

Notes sur la région

Inconnu

Détails

Marques

Mfr's:"DNA/RNA SYNTHESIZER". Mfr's labels:"BIO LOGICALS TORONTO, CANADA/DNA/RNA SYNTHESIZER/MODEL NO. B1 SERIAL NO. B067/VOLTAGE 110/220 WATTS 125/FUSE (AMP) 1½ FREQUENCY 50/60 Hz/MADE IN THE U.S.A. PATENT PENDING/LINE FREQUENCY 48-440 Hz/USE ONLY WITH 250V FUSE/100V/115V/120V/220V/230V/240V/CAUTION-FOR CONTINUED PROCTECTION AGAINST/FIRE HAZARD REPLACE ONLY WITH TYPE 3 AG SLO/ BLO FUSE. [caution is writen in French also].

Manque

Nothing missing.

Fini

A metal case, with synthetic and metal computer components, metal hardware, synthetic keyboard and control buttons, metal connectors on right side of case, on back of case a metal connector, metal fuse and paper.

Décoration

None.